Recent advances in the chemistry of 1,2,4-triazoles: Synthesis, reactivity and biological activities

1,2,4-Triazoles are important heterocyclic motifs that widely found in molecular architectures with medicinal and pharmaceutical properties. Considering the importance of these scaffolds, many works have been published over last few decades. This review provides a focus on synthetic approaches towards 1,2,4-triazole derivatives from common precursors such as amidines, imidates, amidrazones, aryldiazoniums hydrazones decade. also aims to provide an overview triazole biological properties within two years.